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. 2022 May 30;15:916458. doi: 10.3389/fnmol.2022.916458

FIGURE 1.

FIGURE 1

Sal enhances the viability of HEI-OC1 cells after cisplatin damage. (A) HEI-OC1 cells were treated with different Sal concentrations for 24 h. (B) HEI-OC1 cells were pretreated with or without different Sal concentrations (0–100 μM) for 4 h, followed by 20 μM co-treatment for 24 h except for those in the control group. (C) Image of HEI-OC1 cells cultured with different Sal or cisplatin concentrations. Scale bars = 100 μm. Cell viability was measured using the CCK-8 assay. Values are presented as mean ± SEM from independent experiments. *P < 0.05, **P < 0.01, and ***P < 0.001 vs. the control group; &&&P < 0.001 vs. the cisplatin group. ns, no statistical difference; Sal, salubrinal; Cis, cisplatin; con, control.