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. 2022 May 30;13:881275. doi: 10.3389/fmicb.2022.881275

TABLE 2.

Details of KEGG genes whose abundances were significantly different compared to the control fish.

Sl. No Zero-day post-withdrawal
Five-day post-withdrawal
KEGG ID Name of gene % Contribution to dissimilarity KEGG ID Name of gene % Contribution to dissimilarity
1. K03406 mcp (methyl-accepting chemotaxis protein gene) 0.4268 K03406 mcp 0.3137
2. K02030 ABC-PAS (polar amino acid transport system substrate-binding protein gene) 0.2646 K02004 ABC-CDP (putative ABC transport system permease protein) 0.2243
3. K07090 K07090 (uncharacterized protein) 0.248 K07090 K07090 0.2098
4. K00059 fabG {(3-oxoacyl- [acyl-carrier protein] reductase} 0.2186 K02003 ABC-CDA (putative ABC transport system ATP-binding protein) 0.2056
5. K02014 TC.FEV.OM (iron complex outer membrane receptor protein) 0.2168 K02015 ABC.FEV.P (iron complex transport system permease protein) 0.1992
6. K02015 ABC.FEV.P 0.1995 K01992 ABC-2. P (ABC-2 type transport system permease protein) 0.1788
7. K03088 rpoE (RNA polymerase sigma-70 factor, ECF subfamily) 0.1912 K02342 dnaQ (DNA polymerase III subunit epsilon) 0.1756
8. K03704 cspA [cold shock protein (β-ribbon, CspA family)] 0.1905 K03561 exbB (biopolymer transport protein ExbB) 0.1641
9. K02004 ABC.CD.P 0.1839 K06147 ABCB-BAC (ATP-binding cassette, subfamily B, bacterial) 0.1605
10. K02003 ABC.CDA 0.1807 K06076 fadL (long-chain fatty acid transport protein) 0.1598
11. K01992 ABC-2. P 0.1641 K03704 cspA 0.1502
12. K02342 dnaQ (DNA polymerase III subunit epsilon) 0.161 K02016 ABC.FEV.S (iron complex transport system substrate-binding protein) 0.1487
13. K02013 ABC.FEV.A (iron complex transport system ATP-binding protein) 0.1585 K00059 fabG 0.1484
14. K00626 E2.3.1.9, atoB (acetyl-CoA C-acetyltransferase) 0.1567 K02032 ABC.PE.A1 (peptide/nickel transport system ATP-binding protein) 0.1448
15. K02016 ABC.FEV.S 0.1559 K02013 ABC.FEV.A 0.1436
16. K03415 cheV (two-component system, chemotaxis family, chemotaxis protein CheV) 0.1409 K08303 Putative protease 0.1432
17. K02002 proX (glycine betaine/proline transport system substrate-binding protein) 0.1394 K02030 ABC.PA.S 0.1407
18. K03561 exbB (biopolymer transport protein ExbB) 0.1373 K07114 yfbK (Ca-activated chloride channel homolog) 0.1393
19. K02029 ABC.PA.P (polar amino acid transport system permease protein) 0.1321 K03088 rpoE (RNA polymerase sigma-70 factor, ECF subfamily) 0.1367
20. K03310 TC. AGCS (alanine or glycine: cation symporter, AGCS family) 0.1287 K03310 TC. AGCS 0.1364
21. K07025 Putative hydrolase of HAD superfamily 0.1284 K02035 ABC.PE.S (Peptide/nickel transport system substrate-binding protein) 0.1328
22. K03424 tatD (TatD-DNase family protein) 0.128 K02040 PstS (Phosphate transport system substrate-binding protein) 0.1291
23. K06076 fadL (long-chain fatty acid transport protein) 0.1255 K07025 Putative hydrolase of HAD superfamily 0.1275
24. K06147 ABCB-BAC 0.1243 K03424 tatD 0.1268
25. K07107 ybgC (acyl-CoA thioester hydrolase) 0.1235 K03566 gcvA (LysR family transcriptional regulator, glycine cleavage system transcriptional activator) 0.1235
26. K02040 pstS (Phosphate transport system substrate-binding protein) 0.1227 K03415 cheV (Two-component system, chemotaxis family, chemotaxis protein CheV) 0.1141
27. K07114 yfbK 0.1209 K02495 hemN, hemZ (oxygen-independent coproporphyrinogen III oxidase) 0.1113
28. K01626 E 2.5.1.54, aroF, aroG, aroH; 3-deoxy-7-phosphoheptulonate synthase 0.1156 K01626 E2.5.1.54, aroF, aroG, aroH; 3-deoxy-7-phosphoheptulonate synthase 0.1076
29. K03585 acrA, mexA, adeI, smeD, mtrC, cmeA; (Membrane fusion protein, multidrug efflux system) 0.1153 K01990 ABC-2. A; ABC-2 type transport system ATP-binding protein 0.1075
30. K02035 ABC.PE.S 0.1144 K06177 rluA (tRNA pseudouridine32 synthase/23S rRNA pseudouridine746 synthase) 0.1015
31. K00134 GAPDH, gapA (glyceraldehyde 3-phosphate dehydrogenase) 0.1133
32. K02495 hemN, hemZ 0.1131
33. K03566 gcvA 0.112
34. K03408 cheW (Purine-binding chemotaxis protein CheW) 0.1119
35. K02032 ABC.PE.A1 0.1106
36. K03719 lrp (Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein) 0.1101
37. K03924 moxR (MoxR-like ATPase) 0.1084
38. K01990 ABC-2. A 0.1083
39. K06177 rluA 0.1083
40. K03496 parA, soj (chromosome partitioning protein) 0.1075
41. K00020 mmsB (HIBADH; 3-hydroxyisobutyrate dehydrogenase) 0.104
42. K02415 fliL (flagellar FliL protein) 0.103
43. K03321 TC. SULP (sulfate permease, SulP family) 0.1025
44. K03327 TC. MATE, SLC47A, norM, mdtK, dinF; multidrug resistance protein, MATE family 0.1022
45. K08303 Putative protease 0.1005