Table 1.
Participants characteristics at hospital admission
| Exposed to historical lineages | Exposed to VOC Alpha | P-value | |
|---|---|---|---|
| N = 650 | N = 650 | ||
| Age (years), median (range) | 70 (27–100) | 70 (25–101) | |
| Gender—n (%) | |||
| Male | 399 (61.4) | 399 (61.4) | |
| Female | 251 (38.6) | 251 (38.6) | |
| Body Mass Index | 0.20 | ||
| N | 571 | 553 | |
| Median (range) | 26.8 (13.5–67.2) | 27.4 (3.3–76) | |
| Smoker—n (%) | 169 (26.0) | 136 (20.9) | 0.04 |
| Location of initial care—n (%) | 0.12 | ||
| Conventional hospitalization | 560 (86.2) | 539 (82.9) | |
| ICU | 90 (13.8) | 109 (16.7) | |
| Comorbidities, n (%) | 586 (90.1) | 553 (85.0) | 0.004 |
| Cardiovascular disease | 410 (62.9) | 401 (61.6) | 0.57 |
| Chronic lung disease | 102 (15.6) | 74 (11.3) | 0.02 |
| Asthma | 35 (5.3) | 33 (5.0) | 1.00 |
| Chronic kidney disease | 87 (13.3) | 70 (10.7) | 0.11 |
| Chronic liver disease | 21 (3.2) | 12 (1.8) | 0.11 |
| Chronic neurological disease | 115 (17.6) | 88 (13.5) | 0.03 |
| Active cancer | 80 (12.3) | 53 (8.1) | 0.01 |
| Solid organ transplant | 31 (4.7) | 13 (2.0) | < 0.001 |
| Autoimmune disease | 27 (4.1) | 20 (3.0) | 0.15 |
| HIV Infection | 10 (1.5) | 0 (0) | |
| Obesity | 164 (25.2) | 176 (27.0) | 0.54 |
| Diabetes | 197 (30.3) | 182 (27.9) | 0.29 |