TABLE 4.
Univariate analysis of variables related to central lung metastasis (LM)
| Variables | OR | 95%CI | p value |
|---|---|---|---|
| Year of diagnosis | |||
| 2010–2012 | Reference | ||
| 2013–2015 | 1.029 | 0.783–1.351 | 0.8391 |
| a Age(years) | 1.076 | 1.066–1.086 | <0.001 |
| Sex | |||
| Male | 2.296 | 1.743–3.024 | <0.001 |
| Female | Reference | ||
| Laterality | |||
| Solitary | 1.198 | 0.901–1.594 | 0.2145 |
| Multifocal | Reference | ||
| Race | |||
| White | 1.17 | 0.647–2.113 | 0.6039 |
| Others | 0.828 | 0.492–1.393 | 0.4769 |
| Black | Reference | ||
| Grade | |||
| Grade I | Reference | ||
| Grade II | 2.387 | 1.3–4.382 | 0.005 |
| Grade III | 23.438 | 14.431–38.065 | <0.001 |
| Grade IV | 112.747 | 76.005–167.252 | <0.001 |
| T stage | |||
| T1a | Reference | ||
| T1b | 4.615 | 0.959–22.21 | 0.0565 |
| T2 | 7.113 | 1.51–33.495 | 0.0131 |
| T3 | 22.06 | 5.288–92.037 | <0.001 |
| T4a | 211.768 | 51.114–877.355 | <0.001 |
| T4b | 720.477 | 177.296–2927.8 | <0.001 |
| N stage | |||
| N0 | Reference | ||
| N1a | 1.971 | 1.288–3.017 | 0.0018 |
| N1b | 9.483 | 6.962–12.918 | <0.001 |
| Histological type | |||
| PTC | 0.061 | 0.04–0.092 | <0.001 |
| FTC | 0.072 | 0.026–0.202 | <0.001 |
| MTC | 0.015 | 0.01–0.02 | <0.001 |
| ATC | Reference | Reference | Reference |
Abbreviations: ATC, anaplastic thyroid cancer; CI, confidence interval; FTC, Follicular thyroid cancer; LM, lung metastasis; MTC, medullary Thyroid Cancer; NLM, none lung metastasis; OR, odds ratio; PTC, papillary thyroid cancer.
a
Mean continuous variable.