Table 1.
Demographic and clinical characteristics of TCGA set and five validation datasets.
| Clinical feature | TCGA (N = 379) | E-GEOD-17538 (N = 232) | E-GEOD-28722 (N = 125) | E-GEOD-38832 (N = 122) | E-GEOD-39582 (N = 558) | E-GEOD-41258 (N = 141) |
|---|---|---|---|---|---|---|
| Gender (male/female) | 157/131 | 122/110 | – | – | 308/250 | 71/70 |
| Age (mean ± sd) | 65.46 ± 13.26 | 64.73 ± 13.43 | 65.33 ± 12.95 | – | 66.81 ± 13.32 | 64.18 ± 13.48 |
| OS (years, mean ± sd) | 2.61 ± 2.42 | 3.95 ± 2.56 | 5.39 ± 3.53 | 3.37 ± 2.68 | – | – |
| OS status (alive/dead) | 219/69 | 139/93 | 55/70 | 94/28 | – | – |
| DFS (years, mean ± sd) | 2.40 ± 2.31 | 3.65 ± 2.86 | 4.98 ± 3.76 | 3.84 ± 2.77 | 4.06 ± 3.37 | 6.12 ± 4.06 |
| DFS status (0/1) | 203/62 | 145/55 | 92/33 | 83/9 | 380/177 | 105/36 |
| Tumor stage (I/II/III/IV) | 44/112/82/40 | 28/72/76/56 | 23/64/31/5 | 18/35/39/30 | 32/261/201/60 | 27/48/47/19 |
OS: overall survival; DFS: disease-free survival.