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. 2022 Apr 11;247(11):931–944. doi: 10.1177/15353702221082929

Figure 11.

Figure 11.

circRNA/miRNA/mRNA network analysis. Relative expression levels of: (a) hsa_circ_0026646, (b) miR-331-3p, and (c) PLXNB2 in spinal cord tissues determined via qRT-PCR on day 3 post-SCI. (d) The miR-331-3p target site in the 3′UTR of hsa_circ_002664, (e) the miR-331-3p target site in the 3′UTR of PLXNB2, (f) relative luciferase intensity of wild-type (WT) and mutant-type (MT) hsa_circ_0026646 bearing luciferase vectors co-transfected with miR-331-3p expression vectors, (g) relative luciferase intensity of WT and MT PLXNB2 UTR-bearing luciferase vectors co-transfected with miR-331-3p expression vectors, (h) schematic diagram of the hsa_circ_0026646/miR-331-3p/PLXNB2 regulatory axis. **p < 0.01; ***p < 0.001. (A color version of this figure is available in the online journal.)