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. 2022 Apr 17;9(17):2200986. doi: 10.1002/advs.202200986

Figure 1.

Figure 1

Synthesis of LCA/LGG‐LDB and corresponding properties characterization. A) Fluorescent colocalization of coumarin‐labeled LDB, FITC‐labeled chitosan, and Cy5‐labeled LGG in dual probiotics system (Scale bar: 50 µm). B) SEM image of LCA/LGG‐LDB and corresponding region zoom (Scale bar: 5 µm). C) The bacterial colonies of mixed pure LDB and LGG, as well as LCA/LGG‐LDB (105 times dilution). D) Zeta potential of different materials during fabrication of LCA/LGG‐LDB. E) Absorption ability of CSA, LDB, and CSA/LDB toward model BAs of CA. F,G) The retention experiments of LCA/LGG‐LDB with or without chitosan (CS) modification in ileum and colon‐sticked grooves using a microfluids device (Performed in SIF solution, LDB was labeled with Cy5.5). H) In vivo intestinal retention experiments of LCA/LGG‐LDB with or without CS modification (LDB was labeled with Cy5.5).