Table III.
Summary of study results regarding incidence of atopic dermatitis in children and adults from the year 2000 and onwards
| Author, year and reference | Study type | Year of enrollment/study start | Study size (participants, n) | Females (%) | Country | Age, years (range) at enrollment | Age, years at study end | Follow-up | Definition of eczema | Incidence definition | One-year incidence baseline (if applicable) | One-year incidence (95% Cl) | Male incidence | Female incidence |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Anandan C et al., 2009 (87) | Cohort | 1995 | unclear | nr | Scotland | All ages | All ages | 8 | Doctor diagnose and symptoms | Incidence rate of eczema per 1,000 patients per year | nr | 10.2 (9.9–10.6) | 8.8 (8.4–9.2) | 11.6 (11.1–12.1) |
| Cantarutti et al., 2015 (37) | Cohort | 2006–12 | 145,233 | 47.9 | Italy | 0–13 | 0–13 | 6 | Doctor diagnose | Incidence per 1,000 person-years | 14.1 (13.4–14.7) | 16.5 (15.6–17.5) | nr | nr |
| Halkjaer LB et al., 2006 (344) | Birth cohort | 2001 | 411 | 50.6 | Denmark | At age 1 month | 1–2 | Scheduled visits every 6 months. Age at last follow-up 3 years | Doctor diagnose and symptoms | Incidence of atopic dermatitis per year | At 1 year 31% | 10% from age 1 to age 2 years | nr | nr |
| Mebrahtu et al. 2016 (38) | Cohort | 2012–14 | 13,734 | nr | UK | 0 | 3–7 | Median 5.55; range, 0–7.6 | Doctor diagnose or treatment-based algorithm | Incidence rate per 1,000 person-years | nr | 95.6 (93.4–97.9) | 96.5 (93.4–99.7) | 94.8 (91.7–98) |
| Mebrahtu et al., 2016 (38) | Cohort | 2012–14 | 13,734 | nr | UK | 0 | 3–7 | Median 5.55; range, 0–7.6 | Doctor diagnose or treatment-based algorithm | One year incidence, % | 52.4 (51.5–53.2) | nr | nr | |
| Mohn et al., 2018 (378) | Cohort | 2009–15 | 357,451 (2009) 373,954 (2014) |
nr | Norway | <6 | 6–12 | 6 | Doctor diagnose or treatment-based algorithm | Incidence rate per patient-years. | 2009: 0.028 (0.028–0.029) | 2014: 0.034 (0.033–0.035) | nr | nr |
| 2014: 0.073 (0.071–0.075) | ||||||||||||||
| Simpson et al. 2008 (52) | Cohort | 2001–05 | >30 million | nr | UK | All ages | nr | 4 | Doctor diagnose | Age and sex standardized one-year incidence per 1,000 patient-years | 9.6 (9.5–9.7) | 13.6 (13.5–13.7) | nr | nr |
nr: not reported; SD: standard deviation.