Table II.
The recently reported data looking at copy number changes in acral lentiginous melanoma
| Copy number alteration | Reference | n (%) |
|---|---|---|
| Amplification AURKA | Yan et al. 2018 (34) | 472 (25) |
| Amplification GAB2/PAK1 | Chernoff et al. 2009 (35) Yeh et al. 2019 (36) |
122 (22) |
| Amplification CCND1 | Sauter et al. 2002 (37) Yeh et al. 2019 (36) |
122 (21) |
| Amplification CDK4 | Curtin et al. 2005 (38) Yeh et al. 2019 (36) |
122 (22) |
| Deletion NF1 | Liang et al. 2017 (39) | 34 (12) |
| Yeh et al. 2019 (36) | 122 (15) | |
| Inactivation NF1 cooperating factor SPRED1 | Yeh et al. 2019 (36) | 122 (7) |
| Deletion CDKN2A | Liang et al. 2017 (39) | 34 (35) |
| Amplification or point mutation TERT promoter | Liang et al. 2017 (39) | 34 (35) |