Overview of the results obtained for the biomarker of discovery stage.
(A-B) PCA score plots of the untargeted lipidomic result in A) positive ion mode (ESI+) and B) negative ion mode (ESI-). Sample groups are represented by colors: malignant brain gliomas (MBGs, n=72), red; healthy control (NC, n=35), blue; quality control (QC), green. (C-D) Summary of model parameters in terms of specificity, sensitivity and accuracy for the test set in C) positive ion mode (ESI+) and D) negative ion mode (ESI-). N=2000 iterations for SVM model construction; each dot represents data for one iteration of specificity/sensitivity/accuracy in SVM evaluation, and data are presented as means ± SD.