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. 2022 May 24;65(11):7532–7560. doi: 10.1021/acs.jmedchem.2c00281

Figure 2.

Figure 2

PARPi currently in use as anticancer agents and in phase III of clinical trials, and examples of dual PARP1–2/TNKS1–2 inhibitors in clinical studies and TNKS inhibitors in the preclinical phase.