Table 1:
Baseline characteristics and demographic data for women in the top 2.5% of risk for their age (n=113) and age-matched women from the lower 97.5% (n=226).
| Characteristic | BCSC High Risk (Top 2.5% by Age) |
BCSC Lower Risk (Lwr 97.5% by Age) |
P-value |
|---|---|---|---|
|
| |||
| Mean age (range) | 57 (40–73) | 57 (40–73) | Matched |
|
| |||
| Mean BCSC score (SD) | 3.9 (1.3) | 2.0 (0.72) | <0.001 *** |
|
| |||
| BCSC score distribution | <0.001 *** | ||
| Low (0%–<1.00%) | 0 (0%) | 23 (10%) | |
| Average (1.00%–1.66%) | 0 (0%) | 65 (29%) | |
| Intermediate (1.67%–2.49%) | 13 (11%) | 92 (41%) | |
| High (2.50%–3.99%) | 54 (48%) | 46 (20%) | |
| Very high (≥4.00%) | 46 (41%) | 0 (0%) | |
|
| |||
| Breast density distribution | <0.001*** | ||
| BI-RADS a (mostly fatty) | 1 (1%) | 20 (9%) | |
| BI-RADS b | 26 (23%) | 87 (39%) | |
| BI-RADS c | 62 (55%) | 98 (43%) | |
| BI-RADS d (extremely dense) | 24 (21%) | 21 (9%) | |
|
| |||
| First-degree relative with breast cancer | 59 (52%) | 36 (16%) | <0.001 *** |
|
| |||
| History of breast biopsy | 72 (64%) | 88 (39%) | <0.001 *** |
|
| |||
| Mean body mass index (SD) | 23.9 (5.2) | 25.9 (6.1) | 0.003 ** |
|
| |||
| Race: | 0.004** | ||
| White | 92 (81%) | 157 (70%) | |
| Asian | 8 (7%) | 41 (18%) | |
| Black or African American | 0 (0%) | 9 (4%) | |
| Mixed race or other | 13 (12%) | 19 (8%) | |
*
= p < 0.05
**
= p < 0.01
***
= p < 0.001; Standard Deviation (SD)