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. Author manuscript; available in PMC: 2022 Jun 13.
Published in final edited form as: Breast Cancer Res Treat. 2021 Nov 29;191(3):623–629. doi: 10.1007/s10549-021-06451-w

Table 2:

Association between three risk stratification criteria and interval cancers. The three risk stratification criteria included the BCSC top 2.5%, BI-RADS d (extremely dense), or BCSC 5-year cancer risk >4.00% (very high).

Primary Risk Stratification Criteria Interval Cancers in High-risk Group Interval Cancers in Low-risk Group Odds Ratio Confidence Interval P-value
BCSC top 2.5% n=113/339
Avg age=57
Avg BCSC (SD)=3.9 (1.3)
40 (35%) 21 (9%) 6.62 3.28 – 13.4 <0.001***
Alternative Risk Stratification Criteria
BI-RADS d N=45/339
Avg age=51
Avg BCSC (SD)=2.6 (1.2)
18 (40%) 43 (15%) 3.89 1.98 – 7.67 <0.001***
BCSC very high, >4.00% n=46/339
Avg age=62
Avg BCSC (SD)=5.2 (1.1)
15 (30%) 46 (16%) 2.60 1.30 – 5.19 0.007*
*

= p < 0.05

**

= p < 0.01

***

= p < 0.001; Standard Deviation (SD)

= derived from conditional linear regression, unadjusted odds ratio 5.35

= samples not age-matched