Table 2:
Association between three risk stratification criteria and interval cancers. The three risk stratification criteria included the BCSC top 2.5%, BI-RADS d (extremely dense), or BCSC 5-year cancer risk >4.00% (very high).
Primary Risk Stratification Criteria | Interval Cancers in High-risk Group | Interval Cancers in Low-risk Group | Odds Ratio | Confidence Interval | P-value |
---|---|---|---|---|---|
BCSC top 2.5% n=113/339 Avg age=57 Avg BCSC (SD)=3.9 (1.3) |
40 (35%) | 21 (9%) | 6.62† | 3.28 – 13.4 | <0.001*** |
Alternative Risk Stratification Criteria ‡ | |||||
BI-RADS d N=45/339 Avg age=51 Avg BCSC (SD)=2.6 (1.2) |
18 (40%) | 43 (15%) | 3.89 | 1.98 – 7.67 | <0.001*** |
BCSC very high, >4.00% n=46/339 Avg age=62 Avg BCSC (SD)=5.2 (1.1) |
15 (30%) | 46 (16%) | 2.60 | 1.30 – 5.19 | 0.007* |
= p < 0.05
= p < 0.01
= p < 0.001; Standard Deviation (SD)
= derived from conditional linear regression, unadjusted odds ratio 5.35
= samples not age-matched