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Models of Arp2/3 complex bound to CK-666 (A), compound 59, (B), debenzylated metabolite of 59 (C), and compound 69 (D). Induced-fit docking was used to model binding of CK-666 analogs to the structure obtained by co-crystallizing CK-666 with the Arp2/3 complex (PDB code 3UKR).
