Figure 1.

Coefficient for educational attainment as an effect modifier of polygenic susceptibility to cardiovascular risk factors or diseases on the additive and multiplicative scale. Analyses adjusted for age, sex and 40 genetic principal components. Alcohol = drinks per week; BMI = body mass index; LDL-C = low-density lipoprotein cholesterol; smoking = lifetime smoking behaviour; SBP = systolic blood pressure; AF = atrial fibrillation; CHD = coronary heart disease; T2D = type 2 diabetes. Analyses for binary outcomes on the multiplicative scale are presented as log odds ratios