Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison of outcomes according to the exposure to TNFis
| Total (N = 450) | TNFi exposed (N = 233) | TNFi not exposed (N = 217) | P value | |
|---|---|---|---|---|
| Incident cardiovascular disease, n (%) | 20 (4.44) | 6 (2.6) | 14 (6.5) | 0.046 |
| Duration of follow-up, years, median (IQR) | 5.5 (2.9–9.4) | 6.3 (3.4–10.2) | 4.7 (2.8–8.2) | 0.002 |
| Time to events, years, median (IQR) | 3.9 (1.8–7.2) | 3.3 (2.0–8.4) | 4.4 (1.7–7.0) | > 0.999 |
TNFi tumor necrosis factor inhibitor, ESR erythrocyte sedimentation rate, CRP C-reactive protein
