Table 4.
Comparison of the difference in each anthropometric and metabolic parameters variable at pre- and post-lockdown according to metformin taking status.
| Delta values | Without-Metformin, n = 49 | With-Metformin, n = 52 | p |
|---|---|---|---|
| Weight (kg) | 3.3 ± 5.6 (−9.8-18.8) | 2.7 ± 7.6 (−16.3-32.2) | 0.636 |
| Height (cm) | 0.02 ± 0.02 (0.01–0.1) | 0.02 ± 0.03 (0.01–0.16) | 0.735 |
| BMI (kg/m2) | 0.6 ± 1.8 (−4.3-4.6) | 0.2 ± 2.2 (−5.2-7.1) | 0.338 |
| BMI-SD | 0.02 ± 0.4 (−0.9-1.0) | 0.1 ± 0.8 (−5.2-7.1) | 0.341 |
| BMI-percent | 4.2 ± 7.3 (−16.0-23.6) | 2.6 ± 9.2 (−18.1-26.8) | 0.361 |
| BG (mg/dl) | 1.1 ± 13.1 (−31.3-64.0) | 4.9 ± 19.7 (−31.0-89.0) | 0.250 |
| HBA1C (%) | 0.1 ± 0.5 (−1.0-1.0) | −0.1 ± 0.6 (−1.1-1.3) | 0.868 |
| Insulin (μ IU/mL) | −1.7 ± 17.6 (−50.7-36.5) | 7.0 ± 16.9 (−34.1-54.3) | 0.039 |
|
Total Cholesterol (mg/dL) |
0.1 ± 16.8 (−36.0-35.0) | −2.5 ± 41.4 (−96.0-150.0) | 0.740 |
| TG (mg/dL) | 16.1 ± 59.3 (−110.0-182.0) | −9.2 ± 61.5 (−206.0-100.0) | 0.087 |
| HDL (mg/dL) | −1.6 ± 5.9 (−14.8-8.7) | 0.3 ± 5.5 (−11.9-10.8) | 0.160 |
| LDL (mg/dL) | −1.9 ± 14.4 (−26.9-42.5) | 2.7 ± 19.6 (−47.4-53.7) | 0.272 |
| HOMA-IR | 0.3 ± 4.5 (−14.7-10.7) | 1.7 ± 4.0 (−12.7-7.9) | 0.063 |
BMI: Body mass index. BMI-SD: Body mass index- standard deviation. BMI-percent: Body mass index-percent. BG: blood glucose. TG: triglyceride. HDL: high density lipoprotein. LDL: low density lipoprotein. HOMA-IR: homeostasis model assessment-insulin resistance.