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Design with pairing cases with two types of controls. LB and NL denote Lewy bodies and neuronal loss, respectively. Each of the 17 cases (LB+NL+) matched to controls by age, sex, β-amyloid load, and tangles density in the SN. The first type of controls (LB−NL+) matched by neuronal loss. The second type of controls (LB−NL−) reflects the general population and does not have signs of the loss of pigmented neurons.
