Figure 2.

Representative images of H&E staining and TrkA immunostaining of CP patients. (A–F) H&E staining: (A–C) two cases of ACP, showing “finger-like” and “island-like” aggressive growth structures; (D–F) two cases of PCP, showing that the tumor was composed of non-keratinizing squamous epithelium, with visible blood vessels in the interstitial, without invasive growth structure. TE, tumor epithelium; GRT, glial reactive tissue; PE, palisading epithelium; WE, “whorled epithelium” cell groups; SR, stellate reticulum. (G–L) TrkA immunostaining, the signal intensity was moderate and strong and more manifested in the tumor cells that form the “whorled epithelium” structure (G, I) and the palisade epithelium (H) in ACP; the signal was observed in (J) <10% and (K) >50% with moderate and strong intensity or (L) strong and diffuse (51%–80% of neoplastic cells) immunoreactivity in PCP. Panels (A, B, D–F) were captured at 100×, and others were captured at 200× magnification.