Table 4.
Correlation of TrkA, β-catenin, cell cycle markers immunohistochemical score, and BRAF V600E mutation in craniopharyngioma.
TrkA | β-catenin | Cyclin D1 | P16 | Ki-67 | BRAF V600E | ||
---|---|---|---|---|---|---|---|
TrkA | r | 1.000 | 0.088 | −0.070 | 0.338 | −0.441 | 0.023 |
P | – | 0.503 | 0.598 | 0.016 | <0.001 | 0.867 | |
β-catenin | r | 0.088 | 1.000 | 0.497 | 0.000 | −0.272 | −0.666 |
P | 0.503 | – | <0.001 | 0.999 | 0.034 | <0.001 | |
Cyclin D1 | r | −0.070 | 0.497 | 1.000 | -0.148 | 0.2 | −0.222 |
P | 0.598 | <0.001 | – | 0.310 | 0.126 | 0.096 | |
P16 | r | 0.338 | 0.000 | −0.148 | 1.000 | −0.463 | 0.053 |
P | 0.016 | 0.999 | 0.310 | – | 0.001 | 0.732 | |
Ki-67 | r | −0.441 | −0.272 | 0.2 | −0.463 | 1.000 | 0.142 |
P | <0.001 | 0.034 | 0.126 | 0.001 | – | 0.286 | |
BRAF V600E | r | 0.023 | −0.666 | −0.222 | 0.053 | 0.142 | 1.000 |
P | 0.867 | <0.001 | 0.096 | 0.732 | 0.286 | – |
The statistically significant finding was highlighted with bold.