Table 1 Baseline Characteristics of the patients with TS.
| Group 1 | Group 2 | Group 3 | Group 4 | p | |
|---|---|---|---|---|---|
| n | 20 | 27 | 14 | 13 | |
| GH dose | 0.1 | 0.2 | 0.38 | 0 | |
| Chronological age(year) | 7.8±2.4 | 8.0±3.2 | 8.9±3.1 | 7.9±3.7 | 0.75 |
| Karyotype, n (%) | 0.70 | ||||
| 45, X0 | 5 (25%) | 7 (25%) | 3 (20%) | 1 (7.7%) | |
| X abnormal | 13 (65%) | 17 (61%) | 7 (53%) | 1 (76.9%) | |
| Mosaic | 2 (10%) | 3 (11%) | 4 (27%) | 2 (15.4%) | |
| Y chromosome material | 0 | 1 (3%) | 0 | 0 | |
| Height (cm) | 109.6±11.6 | 109.2±14.0 | 115.3±17.0 | 109.5±16.9 | 0.59 |
| HtSDS | –3.23±0.52 | –3.46±0.96 | –3.27±0.89 | –3.23±0.79 | 0.60 |
| MPHSDS | 0.39±0.57 | 0.51±0.93 | 0.29±0.69 | 0.85±0.91c | 0.32 |
| Weight (kg) | 22.58±8.17 | 21.00±8.49 | 25.91±10.77 | 19.57±6.97 | 0.23 |
| BMI (kg/m 2 ) | 18.2±3.5 | 17.0±2.9 | 18.5±2.6 | 15.7±1.5 | 0.03 |
| IGF-1 SDS | –1.10±1.24 | –1.10±1.35 | –0.72±0.80 | –1.15±1.17 | 0.44 |
| HV (cm/year) | 3.2±1.1 | 3.9±1.5 | 3.4±0.9 | 3.9±1.4 | 0.18 |
| BA (year) # | 6.8±2.5 | 6.8±3.0 | 8.2±3.2 | 6.7±3.2 | 0.67 |
| BA-CA (year) # | –0.6±1.0 | −1.3±1.0 | –1.3±1.1 | –1.2±1.1 | 0.19 |
CA: Chronological age; BA: Bone age; HV: Height velocity; BMI: Body mass index; MPH: Mid-parental height; SDS: Standard deviation score. # The numbers of each group with bone age: Group 1 (n=18), Group 2 (n=26), Group 3 (n=8), Group 4 (n=13).