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. 2022 Jun 6;2022:7832983. doi: 10.1155/2022/7832983

Table 2.

Effects of GC on antioxidant enzymes and inflammatory cytokines in PQ-induced RLE-6TN model.

Group Control PQ PQ+GC
Dose (μM) 20 1 10 100
GSH (mg/g pro) 2.82 ± 0.43 1.56 ± 0.37## 1.73 ± 0.16 2.27 ± 0.16∗∗ 2.63 ± 0.09∗∗
NADPH (μM) 13.90 ± 3.62 27.53 ± 1.89## 22.57 ± 1.67∗∗ 17.33 ± 0.94∗∗ 14.95 ± 3.08∗∗
SOD (U/mg pro) 336.81 ± 32.20 149.11 ± 36.49## 205.49 ± 9.34∗∗ 227.81 ± 18.06∗∗ 267.55 ± 10.25∗∗
CAT (U/mL) 6.05 ± 0.43 1.55 ± 0.22## 4.49 ± 0.34∗∗ 3.66 ± 0.27∗∗ 2.59 ± 0.21∗∗
MDA (nM/mg pro) 7.13 ± 1.38 19.34 ± 2.40## 15.38 ± 1.34∗∗ 11.49 ± 1.18∗∗ 8.52 ± 1.96∗∗
LDH (U/L) 643.82 ± 26.17 1205.50 ± 69.82## 940.74 ± 32.66∗∗ 840.44 ± 31.39∗∗ 758.46 ± 29.14∗∗
CK (U/mg pro) 0.55 ± 0.13 1.29 ± 0.16## 0.80 ± 0.11∗∗ 0.70 ± 0.06∗∗ 0.59 ± 0.08∗∗
TNF-α (pg/mL) 4.63 ± 0.28 69.50 ± 6.71## 43.79 ± 3.50∗∗ 23.70 ± 2.07∗∗ 15.22 ± 3.22∗∗
IL-1β (pg/mL) 123.22 ± 15.09 1157.76 ± 63.51## 766.80 ± 61.68∗∗ 468.69 ± 53.03∗∗ 374.28 ± 47.04∗∗
IL-6 (pg/mL) 25.07 ± 2.66 545.68 ± 33.40## 251.92 ± 29.88∗∗ 155.40 ± 25.81 89.86 ± 21.33∗∗

Values were expressed as mean ± S.D. (n = 8). ##P < 0.01 vs. the control group; P < 0.05, ∗∗P < 0.01 vs. the PQ group.