Table 2.
Characteristics of children with CHI and disease-specific data (n = 48)
| Variable | Value | p-value | |||
|---|---|---|---|---|---|
| GAD-7 | PHQ-8 | ULQIE total score | FaBeL total score | ||
| Age* (years; mean, range)b | 8.8 (0.6–22) | .206 | .915 | .446 | .863 |
| Neurodevelopmental impairmenta | 12 (25) | .009c | .024c | .011c | .831 |
| Comorbidities**a | 17 (35.4) | .107 | .083 | .009c | .494 |
| Sibling with chronic diseasea | 5 (10.4) | .175 | .773 | .926 | .423 |
| Using continuous glucose monitoring (CGM)a | 21 (43.8) | .427 | .863 | .977 | .547 |
| Daily blood glucose measurementsa | 28 (58.3) | .211 | .58 | .132 | .928 |
| Prior severe hypoglycemia***a | 26 (54.2) | .468 | .248 | .89 | .509 |
| Weekly hypoglycemia < 60 mg/dLa | 17 (35.4) | .589 | .676 | .203 | .897 |
Values are presented as number (n) and percent (%) if not stated otherwise
GAD-7 Generalized Anxiety Disorder Scale-7, PHQ-8 Patient Health Questionnaire-8, ULQIE Ulm Quality of Life Inventory for Parents of Chronically Ill Children, FaBeL Family Burden Questionnaire
*Children were diagnosed with CHI between 1997 and 2019; **Comorbidities included epilepsy, heart defect, hypothyroidism, diabetes type III, hearing deficit, growth hormone deficiency, kidney disease, atopic disease, scoliosis, AD(H)D, and depression.;***Prior severe hypoglycemia means with seizure or loss of consciousness
aStudent’s t-test
bUnivariate regression
cWorse scores