Table 2.
Remission (n = 108) | Relapse after remission (n = 97)† | |||
---|---|---|---|---|
Unadjusted HR (95% CI) |
Adjusted HR (95% CI)‡ |
Unadjusted HR (95% CI) |
Adjusted HR (95% CI)‡ |
|
Age, 18–39 years |
1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
40–64 | 0.98 (0.62, 1.53) | 1.39 (0.83, 2.32) | 0.75 (0.38, 1.49) | 0.90 (0.40, 2.04) |
65–81 | 0.54 (0.33, 0.89)* | 0.73 (0.40, 1.33) | 0.82 (0.35, 1.93) | 1.21 (0.44, 3.39) |
Men | 1.16 (0.78, 1.73) | 1.42 (0.89, 2.29) | 0.77 (0.42, 1.43) | 0.88 (0.44, 1.76) |
Body mass index, per 1.0 kg/m2 | 0.96 (0.92, 1.01) | 0.95 (0.89, 1.01) | 1.00 (0.92, 1.09) | 1.04 (0.93, 1.16) |
Systolic blood pressure, per 10 mmHg | 0.89 (0.80, 0.99)* | 1.00 (0.85, 1.17) | 0.88 (0.70, 1.10) | 0.87 (0.64, 1.18) |
Serum albumin, per 1.0 g/dL | 0.65 (0.44, 0.95)* | 0.57 (0.37, 0.87)* | 0.73 (0.43, 1.23) | 0.93 (0.52, 1.66) |
eGFR, per 30 mL/min/1.73 m2 | 1.33 (1.10, 1.62)* | 1.43 (1.08, 1.90)* | 0.93 (0.65, 1.32) | 0.91 (0.58, 1.44) |
UP, per 1.0 log g/day or log g/gCr | 1.07 (0.76, 1.52) | 1.25 (0.79, 2.00) | 1.30 (0.72, 2.33) | 1.05 (0.99, 1.13) |
Dipstick hematuria, − or ± |
1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
1+ | 0.86 (0.50, 1.47) | 1.31 (0.71, 2.41) | 0.82 (0.34, 1.96) | 0.64 (0.24, 1.70) |
≥ 2+ | 0.72 (0.47, 1.10) | 0.92 (0.55, 1.53) | 1.40 (0.72, 2.72) | 1.57 (0.69, 3.55) |
Intravenous albumin administration | 0.67 (0.37, 1.23) | 0.97 (0.44, 2.15) | 0.47 (0.11, 1.96) | 0.15 (0.02, 1.25) |
Intravenous mPSL within 1 month of IST | 0.66 (0.42, 1.03) | 0.68 (0.41, 1.11) | 0.96 (0.47, 1.94) | 0.86 (0.40, 1.85) |
Cyclosporine within 1 month of IST | 0.58 (0.31, 1.09) | 0.65 (0.32, 1.33) | 0.64 (0.23, 1.80) | 0.87 (0.28, 2.65) |
CI confidence interval, eGFR estimated glomerular filtration rate, HR hazard ratio, mPSL methylprednisolone, UP urinary protein.
*P < 0.05.
†Including 97 patients with remission of proteinuria within 6 months of IST.
‡Adjusted for all variables listed in the table.