Table 2.
Proportion of patients with lymph node metastasis (pN-positive) according to differentiation, tumor size, and lymphovascular invasion 31.
| a | |||||
|---|---|---|---|---|---|
| No LVI | LVI | ||||
| Differentiation | Tumor size | Total | pN-positive | Total | pN-positive |
| Well or moderate | ≤ 2 cm | 594 | 53 (8.9%) | 134 | 20 (14.9%) |
| ≤ 3 cm | 971 | 121 (12.5%) | 241 | 47 (19.5%) | |
| > 3 cm | 518 | 134 (25.9%) | 156 | 71 (45.5%) | |
| Poor | ≤ 2 cm | 408 | 58 (14.2%) | 102 | 36 (35.3%) |
| ≤ 3 cm | 675 | 119 (17.6%) | 177 | 64 (36.2%) | |
| > 3 cm | 380 | 120 (31.6%) | 80 | 41 (51.2%) | |
| b | |||||
| No LVI | LVI | ||||
| Differentiation | Tumor size | Total | pN-positive | Total | pN-positive |
| Well | ≤ 1 cm | 63 | 1 (1.6%) | 11 | 2 (18.2%) |
| ≤ 2 cm | 200 | 6 (3.0%) | 43 | 3 (7.0%) | |
| ≤ 3 cm | 296 | 10 (3.4%) | 74 | 9 (12.2%) | |
| > 3 cm | 138 | 25 (18.1%) | 55 | 19 (34.5%) | |
| Moderate | ≤ 1 cm | 106 | 12 (11.3%) | 20 | 2 (10.0%) |
| ≤ 2 cm | 394 | 47 (11.9%) | 91 | 17 (18.7%) | |
| ≤ 3 cm | 675 | 111 (16.4%) | 167 | 38 (22.8%) | |
| > 3 cm | 380 | 109 (28.7%) | 101 | 52 (51.5%) | |
a, Well or moderately vs. poorly differentiated tumors. Bolded entries indicate patients meeting criteria for definitive treatment by endoscopic resection according to Japanese (≤ 3 cm) and NCCN (≤ 2 cm) criteria. b, Well vs. moderately differentiated tumors. Italicized entries indicate patients meeting above criteria but excluding moderate differentiation.