Table 3.
Univariable and multivariable logistic regression analysis for lymph node metastasis
| Univariable | Multivariable | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p | OR | 95% CI | p | |
| East vs. West | 0.76 | 0.62–0.93 | 0.007 | 0.89 | 0.64–1.23 | 0.471 |
| Age, years | 1.01 | 1.00–1.01 | 0.124 | |||
| Female vs. male | 1.35 | 1.15–1.58 | < 0.001 | 1.36 | 1.13–1.64 | 0.001 |
| Year of surgery | 1.01 | 0.99–1.02 | 0.428 | |||
| Tumor size, mm | 1.02 | 1.02–1.03 | < 0.001 | 1.03 | 1.02–1.03 | < 0.001 |
| Location | ||||||
| Proximal | 1 | 1 | ||||
| Middle | 1.41 | 1.08–1.85 | 0.012 | 1.28 | 0.94–1.74 | 0.112 |
| Distal | 1.74 | 1.35–2.24 | < 0.001 | 1.78 | 1.34–2.38 | < 0.001 |
| Multiple | 1.19 | 0.59–2.38 | 0.63 | 1.48 | 0.70–3.11 | 0.301 |
| Number of dissected nodes | 1.00 | 1.00–1.01 | 0.102 | |||
| Signet histology | 1.07 | 0.87–1.31 | 0.529 | |||
| Lymphovascular invasion | 2.19 | 1.83–2.62 | < 0.001 | 2.44 | 1.99–2.99 | < 0.001 |
| Differentiation | ||||||
| Well | 1 | 1 | ||||
| Moderate | 2.45 | 1.85–3.23 | < 0.001 | 2.70 | 1.99–3.67 | < 0.001 |
| Poor | 2.83 | 2.14–3.73 | < 0.001 | 3.07 | 2.26–4.18 | < 0.001 |