Table 2.
Population characteristics of the pediatric subjects included in the review
| Study | N (male/female) | Participants | Race/country | Agea | Body weight (kga) |
Subject characteristics | Type of infection | Route |
|---|---|---|---|---|---|---|---|---|
| Thibaut et al.[82] | 26 (15/11) | Patients | France | PNA 24 days (8–88) |
1.42 (0.81–3.25) |
Premature critically ill infants | Mainly CoNS bloodstream infections | IV |
| Li et al. [81] | 112 (65/47) | Patients | China | 1.6 years [0.03–11.9] |
11.0 [2.1–46.0] |
Pediatric patients aged from 0 to 12 years | Confirmed or suspected MR Gram-positive bacterial infection | IV |
| Garcia-Prats et al. [83] | 48 (24/24) | Patients |
South Africa Black (52.1%) Mixed (47.9%) |
4.6 years [0.6–15.3] | NA | HIV infected and uninfected children | MDR-TB | PO |
| Yang et al. [84] | 63 (43/20) | Patients | China |
3.85 years [0.1–15.3] |
15 [4.2–70] |
Critically ill pediatric patients | Staphylococcal infection | IV |
CoNS coagulase-negative staphylococci, CRRT continuous renal replacement therapies, HIV human immunodeficiency virus, IV intravenous, MDR multidrug-resistant, NA not available, PNA post-natal age, PO oral, TB tuberculosis
aValues are expressed as mean ± standard deviation, mean (range) or median [range]