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p63 knockdown in SCC104 shows enrichment of HPV-associated signaling pathways. (A) Western blot analysis of p63 expression in SCC104 and SCC152 cells expressing either p63-targeting shRNAs or a nontargeting shRNA (shCTL). GAPDH: loading control. (B) Volcano plot of DEGs resulting from p63 knockdown in SCC104 cells. (C) KEGG pathway analysis of SCC104 DEGs whose expression showed ≥log2 fold change of 1. (D) Gene set enrichment analysis (GSEA) of DEGs from p63 knockdown in SCC104 cells.
