Figure 3.
To characterize optimal targeting sites of PaeCascade-mediated CRISPRi in S. oneidensis
(A) Targeting sites of designed crRNAs binding different regions of gfp in the genome of the strain S. oneidensis GZ by type I-F PaeCascade-mediated system.
(B) The inhibition efficiency of type I-F PaeCascade system targeting different regions of gfp. The values above the bar indicate the corresponding repression folds. Median GFP levels are normalized to the control strain cr0-GZ. Values and error bars indicate mean ± SEM of three replicates.