Table 1.

Summary statistics of the candidate causal SNPs with log₁₀BF ≥ 2 in the OCA2/HERC2 region on chromosome 15, associated with eye color

Credible Set	rsid	Position in chr 15	Gene	Beta	SE	p value (FE)	p value (RE2)	MAF	I2	Cochran’s Q	Cochran’s Q p value	PIP	Log10BF
1	rs12913832	28365618	HERC2	−1.26	0.02	0	0	0.23	96.25	26.66	243E-07	1.00	13.14
2	rs117007668	28371422	HERC2	0.99	0.08	5.43E-38	8.30E-38	0.01	81.03	5.27	0.02	1.00	5.59
3	rs4778138	28335820	OCA2	0.81	0.03	2.56E-162	1.51E-161	0.13	0.00	0.25	0.62	0.99	5.08
4	rs117744568	28498692	HERC2	0.87	0.06	3.95E-46	1.01E-45	0.02	73.99	3.85	0.05	0.89	4.04
4	rs117743506	28510460	HERC2	0.85	0.06	6.46E-46	1.96E-45	0.02	65.92	2.93	0.09	0.11	2.23
5	rs71467328	28518229	HERC2	−0.48	0.05	5.60E-18	1.13E-17	0.04	27.37	1.38	0.24	0.63	3.36
5	rs1597196	28294922	OCA2	0.42	0.03	3.86E-55	1.27E-54	0.18	63.25	2.72	0.10	0.10	2.17

FE = fixed-effects model; RE2 = random-effects model; MAF = minor allele frequency; I² and Cochran’s Q: meta-analysis heterogeneity indices; PIP = posterior inclusion probability; log₁₀BF ₌ log₁₀ of Bayes Factor.