FIGURE 4.
GA suppressed hepatic TLRS/NF-κB signal pathway in mice induced by LCA. (A) Proteins of liver extracts were evaluated by Western blotting for the determination of TLR2, TLR4, and p-NF-κB-p65 levels. (B) mRNA levels of Il-1β, Il-6, Tnf-α, Ccl2, and Cxcl2 in the hepatic tissues were measured by RT-qPCR. Data are shown as mean ± SD (n = 5). ##p < 0.01 and ##p < 0.001 vs. vehicle group; **p < 0.01 and ***p < 0.001 vs. LCA group.