Table 3.
Number of secondary metabolites clusters (antiSMASH) of Frankia strains Ag45/Mut15 and AgPM24 compared to those of cultivated type strains of Frankia species in clusters 1 to 4
Strain | Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACN14aT | ARgP5T | CpI1T | QA3 | Ag45/Mut15 | AgPM24 | CcI3T | BMG5.1T | BCU110501T | BMG5.12T | G2T | CjT | EAN1pec | EUN1f | M16386T | EuI1cT | Cn3T | DC12 | |
species | alni | canadensis | torreyi | casuarinae | coriariae | discariae | elaeagni | irregularis | soli | asymbiotica | inefficax | saprophytica | ||||||
t1PKS1 | 6 | 9 | 8 | 8 | 9 | 11 | 1 | 6 | 16 | 13 | 6 | 9 | 5 | 9 | 6 | 5 | 2 | 1 |
t2PKS | 1 | 3 | 1 | 3 | 1 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 1 |
t3PKS | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 2 | 0 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 2 |
otherKS | 4 | 4 | 3 | 3 | 3 | 5 | 4 | 1 | 4 | 3 | 6 | 4 | 4 | 6 | 2 | 1 | 2 | 1 |
t1pks-NRPS | 1 | 0 | 1 | 0 | 1 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
NRPS | 3 | 6 | 2 | 2 | 6 | 6 | 0 | 1 | 1 | 2 | 9 | 5 | 3 | 5 | 4 | 2 | 7 | 1 |
terpene | 5 | 3 | 5 | 5 | 4 | 4 | 4 | 3 | 4 | 4 | 3 | 5 | 4 | 4 | 5 | 4 | 4 | 3 |
lanthipeptide | 1 | 1 | 1 | 3 | 0 | 3 | 6 | 2 | 4 | 3 | 2 | 1 | 4 | 3 | 1 | 2 | 1 | 2 |
bacteriocin | 2 | 1 | 2 | 2 | 1 | 2 | 1 | 1 | 2 | 2 | 2 | 2 | 3 | 0 | 3 | 1 | 2 | 0 |
siderophore | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
lassopeptide | 1 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 1 | 2 |
betalactone | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 0 | 1 |
thiopeptide | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
butyrolactone | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
phosphonate | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
arylpolyene | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
nucleoside | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ladderane | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
oligosaccharide | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
resorcinol | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
LAP | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
other | 0 | 2 | 2 | 3 | 1 | 0 | 4 | 1 | 1 | 5 | 1 | 1 | 0 | 1 | 2 | 1 | 5 | 1 |
Total/strain | 27 | 33 | 28 | 33 | 29 | 38 | 26 | 22 | 36 | 35 | 37 | 30 | 27 | 33 | 29 | 23 | 28 | 15 |
1-tnPKS is type ānā PolyKetide Synthase, NRPS is Non Ribosomal Peptide Synthase, LAP is Linear Azole/azoline-containing Peptide.