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Acanthamoeba castellanii and macrophages mannose-purified proteins (MPPs) showed a dose-dependent binding to fungi. Indirect ELISA to analyze the binding of MPPs of A. castellanii and RAW 264.7 macrophages to (A) Candida albicans, (B) Cryptococcus neoformans and (C) Histoplasma capsulatum. (*p < 0.05; **p < 0.001 and ****p < 0.0001).
