Table 3.

Voxel-based morphometry results showing regions with significant grey matter decrease significantly correlating with behavioural disinhibition scores in behavioural variant frontotemporal dementia patients and healthy controls.

Region	Hemisphere	MNI coordinates			t-score
		x	y	z
Compulsivity
Middle frontal gyrus	Left	−27	27	41	3.89
	Right	35	53	21	4.50
Orbitofrontal cortex	Left	−53	36	−6	3.77
	Right	42	32	−21	4.15
Superior temporal gyrus	Right	50	−26	−5	5.51
Middle temporal gyrus	Right	51	−21	−12	5.30
Superior temporal pole	Right	57	14	−8	4.92
Precentral gyrus	Right	54	0	39	4.22
Thalamus	Right	9	−24	15	4.38
Amygdala	Right	27	3	−17	4.22
Insula	Right	44	9	0	4.16
	Left	−35	12	−17	3.80
Social Disinhibition
Superior frontal gyrus	Left	−18	32	38	3.79
		−17	63	21	4.00
	Right	17	66	18	6.32
		23	41	36	3.48
Middle frontal gyrus	Left	−29	30	48	6.36
		−30	56	5	4.51
	Right	45	27	42	4.50
		38	36	38	4.42
Inferior frontal gyrus, pars opercularis	Left	−39	17	11	4.11
	Right	42	14	36	4.84
Inferior frontal gyrus, pars triangularis	Left	−38	20	8	4.54
	Right	56	26	6	4.38
Orbitofrontal cortex	Left	−36	41	−17	4.94
		−8	30	−26	4.49
	Right	41	53	−15	4.34
		8	63	−21	5.88
Superior temporal gyrus	Right	60	−21	−6	4.09
Anterior cingulate gyrus	Left	−5	36	27	4.36
	Right	9	32	29	4.09
Middle cingulate gyrus	Left	−6	−41	53	4.13
	Right	5	−36	47	3.97
Thalamus	Left	−11	−9	11	4.74
	Right	15	−12	12	5.15
Putamen	Left	−29	6	11	3.94
	Right	29	9	9	4.14
		23	6	−11	3.67
Insula	Left	−36	20	6	4.51