Table 3. Multivariable Analysis of the Adjusted Association Between the Quality of the Global Management Before Admission to a Pediatric Intensive Care Unit in Children With a Community-Onset Severe Bacterial Infection and the Outcome.

Variable	Patients, No. (%)a				Multivariable analysis
	Total (N = 159)	Surviving without sequelae (n = 127)	Died (n = 15)	Surviving with sequelae (n = 17)	Surviving without sequelae vs died		Surviving without sequelae vs surviving with sequelae
					aOR (95% CI)	P value	aOR (95% CI)	P value
Age
1 mo to 5 y	113 (71.1)	87 (68.5)	12 (80.0)	14 (82.4)	2.38 (0.55-10.31)	.25	1.92 (0.46-8.09)	.37
≥5 y	46 (28.9)	40 (31.5)	3 (20.0)	3 (17.6)	1 [Reference]		1 [Reference]
Comorbidities
Yes	39 (24.5)	27 (21.3)	7 (46.7)	5 (29.4)	4.49 (1.25-16.09)	.02	1.65 (0.42-6.43)	.47
No	120 (75.5)	100 (78.7)	8 (53.3)	12 (70.6)	1 [Reference]		1 [Reference]
Hemodynamic severity signs at first consultation
Yes	49 (30.8)	35 (27.6)	8 (53.3)	6 (35.3)	1.54 (0.43-5.50)	.51	1.36 (0.40-4.58)	.62
No	110 (69.2)	92 (72.4)	7 (46.7)	11 (64.7)	1 [Reference]		1 [Reference]
Discharge diagnosis
Meningitis	52 (32.7)	42 (33.1)	4 (26.7)	6 (35.3)	1.91 (0.29-12.54)	.50	1.10 (0.24-5.07)	.90
Purpura fulminans	40 (25.2)	30 (23.6)	5 (33.3)	5 (29.4)	2.65 (0.35-19.77)	.34	1.61 (0.31-8.41)	.57
Sepsis with no source	29 (18.2)	22 (17.3)	4 (26.7)	3 (17.6)	3.42 (0.48-24.31)	.22	1.26 (0.22-7.34)	.80
Otherb	38 (23.9)	33 (26.0)	2 (13.3)	3 (17.6)	1 [Reference]	NA	1 [Reference]	NA
Global management
Certainly suboptimal	89 (56.0)	71 (55.9)	3 (20.0)	15 (88.2)	0.16 (0.04-0.65)	.01	5.61 (1.19-26.36)	.03
Optimal	70 (44.0)	56 (44.1)	12 (80.0)	2 (11.8)	1 [Reference]		1 [Reference]

Abbreviation: aOR, adjusted odds ratio.

^a Only children whose global management was assessed optimal or certainly suboptimal were included in these analyses.

^b Other diagnosis includes pulmonary, urinary, osteoarticular, intra-abdominal, cardiac, and soft-tissue severe infections.