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. 2022 May 31;16:905783. doi: 10.3389/fnbeh.2022.905783

Figure 1.

Figure 1

HeterozygousKdm6b knockout mice display impaired sociability. (A) Diagram showing the experimental procedure for the sociability test. (B) Representative heatmap showing the time that wild-type and heterozygote Kdm6b-KO mice spent in exploring the social partner and the non-social object. (C) Quantitative results showing the time that male wild-type and heterozygote Kdm6b-KO mice spent exploring their social partner and object. n = 8 per genotype. P-value calculated using two-way ANOVA test and Sidak’s multiple comparisons test. For the Sidak’s multiple comparisons test: ***p < 0.001, ns: not significant. Error bars in graphs represent mean ± SEM. (D) Quantitative results showing the time that female wild-type and heterozygote Kdm6b-KO mice spent exploring their social partner and object. n = 7 per genotype. P-value calculated using two-way ANOVA test and Sidak’s multiple comparisons test. For the Sidak’s multiple comparisons test: *p < 0.05; **p < 0.01. Error bars in graphs represent mean ± SEM.