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. 2022 May 31;12:892195. doi: 10.3389/fonc.2022.892195

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Copyright © 2022 Klepinin, Miller, Reile, Puurand, Rebane-Klemm, Klepinina, Vija, Zhang, Terzic, Dzeja and Kaambre

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sample preparation workflow for ¹⁸O-labelling based phosphometabolomics and metabolite ¹⁸O-labeling sequence. AK, adenylate kinase; CK, creatine kinase; Cr, creatine, CrP, creatine phosphate; Pi, inorganic phosphate; OxPhos, oxidative phosphorylation; prep-LC, preparative liquid chromatography; GC-MS, gas chromatography-mass spectrometry.