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. 2022 May 31;13:881708. doi: 10.3389/fphar.2022.881708

FIGURE 2.

FIGURE 2

CD38 expression using Immunohistochemistry (IHC) staining for CD38 antibody and DAPI (A,B), Western Blotting (C), and CD38 enzymatic activity (D,E) in the brains of WKY and SHRSP. Group comparisons are completed in the figure using Fisher’s LSD test post ANOVA. Results indicate significantly increased CD38 expression and enzymatic activity in SHRSP compared to WKY at 7 and 24 weeks of age. Differences were also detected in some comparisons according to age as indicated in the figure. DAPI: 4,6-diamidino-2-phenylindole; SHRSP: spontaneously hypertensive stroke-prone rats; WKY: wistar-kyoto rat; ns: not statistically significant; (*) p < 0.05, (**) p < 0.01, (***) p < 0.001. Data represent the means and standard errors.