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. 2022 May 31;13:881708. doi: 10.3389/fphar.2022.881708

FIGURE 3.

FIGURE 3

Localization of CD38 expression in the brain of SHRSP. Immunofluorescence is shown in the brain of 24-week-old rats. CD38 expression was seen on the endothelial cells (A) and astrocytes (B) as manifested by colocalizing with eNOS and GFAP antibodies, respectively. A lesser degree of expression was seen on the microglia using co-localization with Iba-1 (C). eNOS: endothelial nitric oxide synthase; GFAP: Glial fibrillary acidic protein; Iba1: ionized calcium binding adaptor molecule 1; SHRSP: spontaneously hypertensive stroke-prone rats.