Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 31;13:817552. doi: 10.3389/fgene.2022.817552

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Cai, Jing, Wen, Guo and Xue.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Protein-protein interaction (PPI) network and enrichment bar graph for methylation-related DEGs. (A) Enrichment bubble graph for hypermethylated downregulated genes. (B) Enrichment bubble graph for hypomethylated upregulated genes. (C) KEGG enrichment bubble chart of hypermethylated downregulated genes and hypomethylated upregulated genes. (D) PPI network of hypermethylation and low-expression genes between cancer and adjacent samples from LUAD patients (only displays the 10 hub genes and the expanded subnetwork identified by the cytoHubba app in Cytoscape). (E) PPI network of hypomethylation and high-expression genes between cancer and adjacent samples from LUAD patients (only displays the 10 hub genes and the expanded subnetwork identified by the cytoHubba app in Cytoscape).