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. 2022 Jun 10;219(8):e20200418. doi: 10.1084/jem.20200418

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© 2022 Zhang et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure S2. — Age-related changes in grip and behavior. (A) Latency to fall off a rotating rod (s) in the rotarod test of C57BL/6J background WT and Ccl17-KO mice at 4 mo (young) or 21 mo (aged; n = 7–8 biological replicates). (B) Open-field test. Total distance traveled (m) and center time (s) for each 5-min block of testing of C57BL/6J background WT and Ccl17-KO mice at 4 mo (young) or 21 mo (aged; n = 7–8 biological replicates). (C and D) The number of arm entries (C) and spontaneous alternation score (D) were measured in the Y-maze spontaneous alternation test to evaluate the working spatial memory of C57BL/6J background WT and Ccl17-KO mice at 4 mo (young) or 21 mo (aged; n = 7–8 biological replicates). All data are presented as the mean ± SD. Statistical significance was tested using one-way ANOVA followed by Bonferroni post hoc test (A–D). *, P < 0.05; **, P < 0.01; ***, P < 0.001.