Skip to main content
. 2022 Jun 10;219(8):e20200418. doi: 10.1084/jem.20200418

Figure S3.

Figure S3.

Basic characteristics of WT and Ccl17-KO mice in age-related and Ang II–induced models. (A–C) The body weight (A), heart rates (B), and blood pressures (C) of C57BL/6J background WT mice and Ccl17-KO mice at 4 mo (young) and 21 mo (aged; n = 11–12 biological replicates). (D) The ratios of HW/BW of young (4-mo-old) or aged (21-mo-old) C57BL/6J background WT mice and Ccl17-KO mice (n = 11–12 biological replicates). (E) The ratios of lung weight to body weight (LW/BW) or lung weight to TL (LW/TL) of C57BL/6J background WT and Ccl17-KO mice at 4 mo (young) or 21 mo (aged; n = 11 biological replicates). (F) Heart rates of 8–12-wk-old C57BL/6J background WT and Ccl17-KO mice infused with saline or Ang II for 4 wk (n = 14–15 biological replicates). (G) Systolic and diastolic blood pressures of 8–12-wk-old C57BL/6J background WT and Ccl17-KO mice infused with saline or Ang II for 4 wk (n = 14–15 biological replicates). All data are presented as the mean ± SD. Statistical significance was tested using one-way ANOVA followed by Bonferroni post hoc test (A, B, and D–G) or nonparametric Kruskal-Wallis test with post Dunn’s multiple comparisons test (C). *, P < 0.05; **, P < 0.01; ***, P < 0.001.