Table 1.
Characteristic | Primary ciliary dyskinesia (n = 47) | Control (n = 25) | P value [95% CI] |
---|---|---|---|
Age, mean ± SD, y | 10.4 ± 4.92 | 10.1 ± 4.56 | .72 |
Male sex | 25 (53.2%) | 14 (56%) | .82 |
Nonwhite ethnicity | 22 (46.8%) | 10 (40%) | .58 |
Organ laterality defect | 23 (48.9%) | 0 (0%) | <.01b |
Otologic reported symptoms | |||
Hearing loss | 18 (38) | 2 (8) | <.01b |
Vertigo and imbalance | 9 (19) | 0 (0) | .02b |
Otalgia | 6 (13) | 4 (16) | .71 |
Ear fullness | 10 (21) | 1 (4) | .05 |
Chronic or recurrent otorrhea | 11 (23) | 1 (4) | .035b |
Mean No. of acute otitis media annually | 1.6 ± 2.75 | 0.96 ± 1.59 | .62 [−0.55 to 1.8] |
Mean No. of ear tube insertions | 2.04 ± 1.93 | 0.44 ± 0.65 | <.01b [0.8 to 2.39] |
Sinonasal and airway reported symptoms | |||
Congestion | 39 (83) | 0 (0) | <.01b |
Pain or pressure | 9 (19) | 0 (0) | .02b |
Obstruction | 31 (66) | 3 (12) | <.01b |
Postnasal drip | 35 (74) | 0 (0) | <.01b |
Anosmia | 11 (23) | 0 (0) | <.01b |
Rhinorrhea | 35 (74) | 0 (0) | <.01b |
Epistaxis | 11 (23) | 5 (20) | .74 |
Cough | 40 (85) | 0 (0) | <.01b |
Snoring | 23 (49) | 2 (8) | <.01b |
Mouth breathing | 33 (70) | 2 (8) | <.01b |
Mean No. of acute sinusitis in past 2 years | 0.04 ± 0.2 | 0.12 ± 0.43 | .04b [0.0736 to 0.22] |
Mean No. of acute tonsillitis in past 2 years | 0.1 ± 0.6 | 0.4 ± 0.65 | .056 [−0.6 to 0.01] |
Chronic medical therapy | |||
Nasal steroids | 11 (23) | 0 (0) | <.01b |
Saline spray or drops | 16 (34) | 1 (4) | <.01b |
Nasal decongestants | 1 (2) | 0 (0) | .46 |
Proton pump inhibitors | 1 (2) | 0 (0) | .46 |
Surgical history | |||
Adenoidectomy | 15 (32) | 4 (16) | .15 |
Past sinus surgery | 3 (6) | 0 (0) | .20 |
Values are presented as number (%) unless otherwise indicated.
Statistically significant; 95% CI is provided for t test results.