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. Author manuscript; available in PMC: 2022 Jun 14.
Published in final edited form as: Otolaryngol Head Neck Surg. 2021 Jun 22;166(3):540–547. doi: 10.1177/01945998211019320

Table 1.

Items Included in the Standardized Clinical History and Their Reporting.a

Characteristic Primary ciliary dyskinesia (n = 47) Control (n = 25) P value [95% CI]
Age, mean ± SD, y      10.4 ± 4.92  10.1 ± 4.56   .72
Male sex         25 (53.2%)     14 (56%)   .82
Nonwhite ethnicity         22 (46.8%)     10 (40%)   .58
Organ laterality defect         23 (48.9%)    0 (0%) <.01b
Otologic reported symptoms
 Hearing loss         18 (38)    2 (8) <.01b
 Vertigo and imbalance        9 (19)    0 (0)   .02b
 Otalgia        6 (13)    4 (16)   .71
 Ear fullness         10 (21)    1 (4)   .05
 Chronic or recurrent otorrhea         11 (23)    1 (4)   .035b
 Mean No. of acute otitis media annually        1.6 ± 2.75  0.96 ± 1.59   .62 [−0.55 to 1.8]
 Mean No. of ear tube insertions      2.04 ± 1.93  0.44 ± 0.65 <.01b [0.8 to 2.39]
Sinonasal and airway reported symptoms
 Congestion         39 (83)    0 (0) <.01b
 Pain or pressure        9 (19)    0 (0)   .02b
 Obstruction         31 (66)    3 (12) <.01b
 Postnasal drip         35 (74)    0 (0) <.01b
 Anosmia         11 (23)    0 (0) <.01b
 Rhinorrhea         35 (74)    0 (0) <.01b
 Epistaxis         11 (23)    5 (20)   .74
 Cough         40 (85)    0 (0) <.01b
 Snoring         23 (49)    2 (8) <.01b
 Mouth breathing         33 (70)    2 (8) <.01b
 Mean No. of acute sinusitis in past 2 years      0.04 ± 0.2  0.12 ± 0.43   .04b [0.0736 to 0.22]
 Mean No. of acute tonsillitis in past 2 years        0.1 ± 0.6    0.4 ± 0.65   .056 [−0.6 to 0.01]
Chronic medical therapy
 Nasal steroids         11 (23)    0 (0) <.01b
 Saline spray or drops         16 (34)    1 (4) <.01b
 Nasal decongestants        1 (2)    0 (0)   .46
 Proton pump inhibitors        1 (2)    0 (0)   .46
Surgical history
 Adenoidectomy         15 (32)    4 (16)   .15
 Past sinus surgery        3 (6)    0 (0)   .20
a

Values are presented as number (%) unless otherwise indicated.

b

Statistically significant; 95% CI is provided for t test results.