TABLE 3.
Univariate and multivariate analyses for T3‐T4 GSCC patients
| Factors selected | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| Hazard ratio (95% CI) | P‐value | Hazard ratio (95% CI) | P‐value | |
| Age | .430 | |||
| ≥60 vs. <60 | 1.244 (0.724–2.136) | |||
| Sex | .461 | |||
| Female vs. male | 2.172 (0.276–17.128) | |||
| History of smoking | .312 | |||
| Yes vs. no | 1.380 (0.739–2.577) | |||
| History of alcohol drinking | .840 | |||
| Yes vs. no | 1.057 (0.617–1.810) | |||
| History of hypertension | .688 | |||
| Yes vs. no | 1.147 (0.587–2.242) | |||
| History of diabetes | .877 | |||
| Yes vs. no | 0.905 (0.257–3.185) | |||
| T stage | .015 | .602 | ||
| T4 vs. T3 | 2.046 (1.152–3.634) | 1.178 (0.635–2.185) | ||
| Differentiation | .032 | .025 | ||
| Low/moderate vs. high | 1.858 (1.056–3.269) | 1.951 (1.086–3.505) | ||
| Maximum tumor diameter (MTD) | .000 | .032 | ||
| >2.0 cm vs. ≤2.0 cm | 4.839 (2.139–10.943) | 2.649 (1.085–6.469) | ||
| Tumor invasive depth | .000 | .005 | ||
| ≥1.0 cm vs. <1.0 cm | 6.568 (2.565–16.818) | 4.267 (1.558–11.689) | ||