Figure 3.

In vivo study timeline. Piglets were acclimatized, and skin biopsies were collected prior to immunization. Piglets in treatment groups were primed at week 0 and then boosted at week 14 post-prime with the Ad-pp220 cocktail as shown in Table 1. Negative control piglets were similarly primed and boosted, but with Ad-Luciferase. Pigs from all the groups were terminated after week 8 post-boost. Blood samples were collected weekly post-prime and post-boost for PBMCs and sera. During termination, blood samples were collected, and spleens were harvested.