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. 2022 May 31;9:921481. doi: 10.3389/fvets.2022.921481

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Copyright © 2022 Zajac, Sangewar, Lokhandwala, Bray, Sang, McCall, Bishop, Waghela, Kumar, Kim and Mwangi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytotoxic T-lymphocyte (CTL) responses against the pp220 antigens. At four weeks post-boost, p5-34-14-37-, p150-I-, and p150-II-specific CTL responses in PBMCs collected from (A) Ad-pp220-ENABL^®-immunized; or (B) Ad-pp220-ZTS-01-immunized pigs were evaluated at effector to target ratios of 25:1 and 50:1 using the standard ⁵¹Cr release assay. Data are represented as the percent specific lysis against each antigen and a negative-control FMDV antigen (Ag). Mean responses for each antigen are denoted by bars.