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. Author manuscript; available in PMC: 2022 Jun 14.
Published in final edited form as: Clin Infect Dis. 2021 Nov 2;73(9):e2729–e2738. doi: 10.1093/cid/ciaa806

Table 2.

Incidence Rate Estimates Among Acute Gastroenteritis Case Patients (Inpatients and Outpatients), by Pathogen and Overall, July 2016 to June 2018

Setting Rate per 100 000 Population (95% CI)a
AGE Ciostridioides difficile Norovirus Campylobacter Shigeiia/EIEC Saimoneiia Rotavirus

Inpatients
Overall 380 (363–396) 71.3 (61.3–82.3) 19.4 (13.9–26.2) 14.7 (9.4–20.4) 8.4 (4.7–12.6) 6.8 (3.7–10.5) 5.8 (2.6–9.4)
Attributable Fraction (AF)b ... 43 (41.5–44.7) 13.8 (10.7–14.8) 12.8 (0–15.8) 8.4 (4.7–12.6) 5.9 (0–76) 5.8 (2.6–9.4)
Age group
 <65 y 315 (293–334) 56.2 (44.5–68.8) 14.3 (76–21.8) 10.1 (5–15.9) 10.1 (5–15.9) 5.9 (1.7–10.1) 5.0 (1.7–9.2)
 ≥65 y 459 (433–484) 90.6 (70.9–110) 26.3 (15.8–38.1) 21 (11.8–32.8) 5.3 (1.3–11.8) 79 (2.6–14.4) 6.6 (1.3–11.8)
Exposure setting
 Community onset 218 (207–230) 55.6 (45.6–64) 18.3 (12.3–23.9) 13.6 (8.9–18.3) 79 (4.2–11.5) 6.8 (3.1–11) 5.8 (2.6–9.4)
 Hospital onset 388 (347–430) 114 (79.6–145) 76 (0–19) 76 (0–19) 3.8 (0–11.4) 0 (0–0) 0 (0–0)
Season
 Winter (November-April) 504 (474–532) 84.8 (673–101) 29 (18.6–39.5) 12.8 (5.8–19.7) 10.4 (4.2–16.6) 5.8 (1.2–11.6) 11.6 (5.8–19.7)
 Summer (May-October) 375 (351–402) 65.4 (50.9–80.0) 12.5 (6.2–19.7) 177 (9.3–26) 7 (2.3–12.8) 8.3 (3.1–14.5) 1.0 (0–3.1)
Surveillance year
 July 2016 to June 2017 268 (249–288) 46 (34.0–58.1) 15 (8–23) 10 (4.6–16.4) 6.4 (1.8–11.8) 4.6 (.9–9.1) 8.0 (3.0–14)
 July 2017 to June 2018 479 (453–503) 94.6 (76.7–111) 23.1 (14.7–32.6) 16.3 (9.6–24.9) 8.6 (3.8–15.3) 76 (2.9–13.4) 3.2 (0–74)
Outpatients
Overall 2715 (2674–2755) 285 (207–361) 291 (226–366) 140 (91.6–194) 80.8 (43.1–121) 32.3 (10.8–59.2) 80.8 (48.5–119)
Age group
 <65 y 3100 (3041–3158) 272 (188–371) 329 (225–441) 169 (93.9–254) 112.7 (56.4–178) 28.2 (0–65.7) 103 (47–159)
 ≥65 y 2247 (2192–2302) 310 (207–426) 245 (155–349) 103 (38.7–181) 38.7 (0–775) 38.7 (0–90.4) 51.7 (12.9–103)
Season
 Winter (November-April) 3369 (3321–3417) 455 (313–611) 542 (381–703) 147 (73.2–234) 128 (56.9–213) 28.4 (0–71.1) 142 (56.9–227)
 Summer (May-October) 2854 (2810–2899) 225 (139–321) 253 (149–372) 238 (133–357) 64.1 (21.4–117) 42.8 (5.3–85.5) 53.5 (10.7–102)
Surveillance year
 July 2016 to June 2017 2517 (2460–2574) 306 (178–428) 242 (129–354) 113 (48.4–202) 48.4 (0–112) 16.1 (0–48.4) 145 (56.5–242)
 July 2017 to June 2018 2892 (2835–2950) 283 (200–374) 324 (233–420) 158 (91.4–224) 99.7 (49.9–157) 41.6 (8.3–83.1) 49.9 (16.6–91.4)

Abbreviations: AGE, acute gastroenteritis; CI, confidence interval; EIEC, enteroinvasive Escherichia coli.

a

CIs for AGE outpatient estimates and inpatient community and hospital-onset inpatient estimates were calculated assuming Poisson distribution. Remaining estimates including pathogen-specific CIs calculated using bootstrapping.

b

The attributable fraction (AF) was calculated for inpatient pathogens based on the odds ratio (OR) of that pathogen’s prevalence among case patients and controls, using the following formula: (OR −1)/OR. The AF is an estimate of the percentage of AGE cases that can be attributed to infection with the pathogen of interest. (The AF was not calculated for other inpatient variables, owing to the small sample size for controls after stratification.)