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. 2022 May 30;10:890420. doi: 10.3389/fpubh.2022.890420

Table 3.

Previously identified potential salivary miRNA biomarkers associated with persistent post–concussive symptoms (PPCS).

Association in other studies Associated with PPCS in our cohort? P–value in current study
Previously identified salivary miRNA that are expressed in current study
hsa–miR−203a−5p PPCS (19) Yes 0.00319
hsa–miR−148–3p PPCS (19) No hsa–miR−148a−3p: 0.28106 hsa–miR−148b−3p: 0.52139
hsa–miR−1246 PPCS (19) No 0.85564
Previously identified salivary miRNA that are not expressed or not measured in current study
hsa–miR−320c−1 PPCS (18) No NA
hsa–miR−133a−5p PPCS (18) No NA
hsa–miR−769–5p PPCS (18) No NA
hsa–let−7a−3p PPCS (18) Not measured NA
hsa–miR−100–5p PPCS (19) No NA
hsa–miR−148a−5p PPCS (19) Not measured NA
hsa–miR−423–5p PPCS (19) No NA
hsa–miR−92b−3p PPCS (19) No NA
hsa–miR−1307–3p PPCS (18) No NA
Salivary miRNA significantly expressed in current study that were not previously identified
hsa–miR−548y NA Yes 0.00015
hsa–miR−585–3p NA Yes 0.00015
hsa–miR−378h NA Yes 0.00015
hsa–miR−1323 NA Yes 0.00015
hsa–miR−183–5p NA Yes 0.00015
hsa–miR−199a−3p+hsa–miR−199b−3p NA Yes 0.00015
hsa–miR−301a−5p NA Yes 0.00148
hsa–miR−626 NA Yes 0.00244
hsa–miR−888–5p NA Yes 0.00518
hsa–miR−548e−5p NA Yes 0.00696
hsa–miR−200a−3p NA Yes 0.00789
hsa–miR−95–3p NA Yes 0.01010