Table 1.
Demographic characteristics of 73 patients who underwent microscopic transsphenoidal surgery for giant pituitary adenomas.
| Variable | No. |
|---|---|
| Age (years) | 49.05 ±12.48 |
| Sex | |
| Male | 46 (63%) |
| Female | 27 (37%) |
| Tumor size (mm) | 47.11 ±7.09 |
| Suprasellar tumor height (mm) | 19.65 ±7.92 |
| Proportion of suprasellar tumor volume (%) | 44.38 ±15.54 |
| Tumor texture | |
| Soft | 60 (82.2%) |
| Tough | 13 (17.8%) |
| Tumor blood supply | |
| Poor | 24 (32.9%) |
| Good | 49 (67.1%) |
| Tumor boundary adhesion | |
| No | 36 (49.3%) |
| Yes | 37 (50.7%) |
| Intraoperative confirmed CSI | |
| No | 36 (49.3%) |
| Yes | 37 (50.7%) |
| Preoperative hydrocephalus | |
| No | 58 (79.5) |
| yes | 13 (20.5) |
| Intraoperative cerebrospinal fluid leakage | |
| No | 57 (78.1%) |
| Yes | 16 (21.9%) |
| Tumor lobulation | |
| No | 44 (60.3%) |
| Yes | 29 (39.7%) |
| Invasion of middle cranial fossa | |
| No | 52 (71.2%) |
| Yes | 21 (28.8%) |
| Suprasellar extension grade (SIPAP) | |
| 0–2 grade | 28 (38.4%) |
| 3–4 grade | 45 (61.6%) |
| Anterior and posterior sellar extension grade (SIPAP) | |
| 0 grade | 51 (69.9%) |
| 1 grade | 22 (30.1%) |
| Knosp grade | |
| 0–2 grade | 21 (28.8%) |
| 3–4 grade | 52 (71.2%) |
| Pathological type | |
| Gonadotroph adenoma | 44 (60.3%) |
| Lactotroph adenomas | 10 (13.7%) |
| Somatotroph adenomas | 5 (6.8%) |
| Corticotroph adenomas | 5 (6.8%) |
| Thyrotroph adenomas | 1 (1.4%) |
| Null cell adenoma | 1 (1.4%) |
| Plurihormonal adenomas | 7 (9.6%) |
CSI, cavernous sinus invasion; SIPAP, suprasellar, infrasellar, parasellar, anterior, and posterior; Values are expressed as mean ± standard deviation, median (interquartile range), or number (%). Significant P-values are shown in bold.