Table 4. Interference of biotin and haemolysis on the hs-assay on the Atellica IM analyser.
|
Sample
Biotin conc. (µg/L) |
hs-Tn
Target conc. (ng/L) |
hs-Tn
Average |
Bias (%) |
Sample
Hb* conc. (g/L) |
hs-Tn
Target conc. (ng/L) |
hs-Tn
Average |
Bias (%) |
|---|---|---|---|---|---|---|---|
| Control (100) | 50 | 50.90 | / | Control (1.5) | 50 | 46.86 | / |
| Spike (100) | 50 | 50.38 | -1.03 | Spike (1.5) | 50 | 48.21 | 2.81 |
| Control (1500) | 50 | 48.49 | / | Control (5.0) | 50 | 49.79 | / |
| Spike (1500) | 50 | 48.80 | 0.65 | Spike (5.0) | 50 | 44.70 | -11.39 |
| Control (100) | 100 | 99.19 | / | Control (1.5) | 100 | 96.31 | / |
| Spike (100) | 100 | 97.76 | -1.46 | Spike (1.5) | 100 | 95.86 | -0.46 |
| Control (1500) | 100 | 93.99 | / | Control (5.0) | 100 | 96.43 | / |
| Spike (1500) | 100 | 92.455 | -1.67 | Spike (5.0) | 100 | 94.375 | -2.18 |
| *Hb – Haemoglobin. hs-Tn – high sensitive troponin. conc. – concentration. Recovery was expressed in %. | |||||||